This is more likely in adults and children who already have existing heart disease. Heart problemsĪmphetamines may cause heart problems, including a heart attack or other life-threatening situations that can lead to death. If your child isn’t growing or is losing weight on Xelstrym, talk to their healthcare provider. In the study of Xelstrym, some children experienced weight loss. Stimulants have been linked to slowed growth and weight loss in children. This helps avoid the high that can occur when a medication is quickly absorbed into the bloodstream. Long-acting medications are released into the blood gradually. In general, long-acting stimulants are less likely to cause dependence and misuse than short-acting ones. There are no refills allowed on Schedule II prescriptions, which means you need a new prescription each time you run out. Controlled substances have a high potential for dependence and misuse. Prescription stimulants like Xelstrym are Schedule II controlled substances. It’s important to know about these risks so you know what to watch out for while you or your child is prescribed Xelstrym. Pain and itchiness where the patch was appliedĭoes Xelstrym have any serious side effects? Side effects may vary between children and adults, but possible side effects include: Like all medications, side effects may occur with Xelstrym. What are the known side effects of Xelstrym? Xelstrym is considered to be similar to lisdexamfetamine, so these studies were used to evaluate Xelstrym’s effectiveness in adults. But another amphetamine - lisdexamfetamine - is well-studied in adults. The study found that Xelstrym provided better control of ADHD symptoms compared to placebo (a patch with no medication in it).Īt the time of Xelstrym’s FDA approval, there aren’t studies evaluating Xelstrym’s efficacy in adults. Their dose was raised as needed to manage ADHD symptoms. Xelstrym was started in 110 children with ADHD. An RCT is one of the best types of studies to determine if a medication works. Xelstrym was studied in 6 to 17 year olds in a randomized controlled trial (RCT). If it comes off completely, apply a new patch. If the edges of the patch peel off, press down on the patch to reattach it. Heat can cause Xelstrym to be absorbed more quickly, which is dangerous. When applying, your skin should be dry without any skincare products on it.Īvoid placing Xelstrym on hairy areas of the body.Īvoid using external heat (like heating pads, electric blankets) where Xelstrym is placed. To avoid skin irritation, change where you apply Xelstrym each time. Other tips for applying Xelstrym include: The sides and back of your belly (between your ribs and hips) Don’t use more than one patch per 24 hours. For those with kidney failure - also known as end stage renal disease (ESRD) - the maximum recommended dose is 9 mg.Īpply Xelstrym 2 hours before you want to see effects, and take it off within 9 hours of placing it. In people with severe kidney problems, the maximum dose is 13.5 mg. For most children and adults, the recommended maximum dose is 18 mg. In children, the dose can be raised gradually by 4.5 mg on a weekly basis. For adults, the 9 mg patch is recommended as a starting dose. Xelstrym is available in four different patch strengths:įor children ages 6 to 17 years old, it’s recommended to start with the 4.5 mg patch. A higher level of these chemicals in the body can lead to elevated alertness, energy, and attention, which may be how they help treat ADHD. Dopamine affects how we react to rewarding experiences. Norepinephrine plays a role in regulating our attention span and response to stress. People with ADHD have an altered amount of these chemicals in the brain. These chemicals - norepinephrine and dopamine - help manage our mood and attention. It’s not completely clear how amphetamines like Xelstrym treat ADHD, but we know that they raise the amount of certain chemicals in the brain. That makes Xelstrym the first patch to be FDA-approved to treat ADHD in adults. The other prescription patch for ADHD is Daytrana (methylphenidate).ĭaytrana is only approved to treat ADHD in children and teens age 6 to 17 years old. Xelstrym is the first FDA-approved amphetamine patch that treats ADHD. Prescription stimulants are divided into two categories: amphetamines (like Adderall) and methylphenidate (like Ritalin). It’s FDA-approved for use in adults and children ages 6 and older. When you apply the patch, the medication is absorbed into your body through your skin. Xelstrym is a transdermal patch that treats ADHD.
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